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Nurse Practitioners salary in St. Louis, MO

Nurse Practitioners in the St. Louis, MO-IL metropolitan area earn a median of $131,580 a year, an average of $135,550. About 3,430 people work in this occupation there. Figures are from the May 2025 U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics (OEWS).

Nurse Practitioners pay at a glance

Annual median wage
$131,580
Half earn more, half earn less
Annual mean wage
$135,550
Pulled up by top earners
10th percentile
$108,340
Bottom of the range
90th percentile
$164,280
Top of the range
People employed
3,430
In St. Louis metro area
Rent share of median wage
8.9%
Median rent ÷ median wage

What this wage buys in St. Louis

Rent from the ACS 2019-2023 5-Year Estimates, compared with the wage above

Median gross rent
$978
per month, in St. Louis, MO
Income needed for median rent
$39,100
Keeps rent at 30% of gross pay
Median nurse practitioners wage
$131,580
236.5% above income needed for median rent
Rent as share of this wage
8.9%
12 months rent ÷ median wage
City median household income
$55,279
All households, not one occupation

Occupations are not paid the same everywhere, and this page does not explain why. It reports what the survey measured for the St. Louis area. Read the St. Louis, MO cost of living page for rent, income and the price level, or the methodology for how the numbers are compiled.

Nurse Practitioners pay in other cities

Median annual wage, same occupation, same survey

Lincoln, NE
-5.4%
Median $124,440
Mean $124,660
Employed 320
Jersey City, NJ
+24.1%
Median $163,340
Mean $162,620
Employed 21,680
Anchorage, AK
+19.6%
Median $157,430
Mean $150,380
Employed 410
Durham, NC
+0.5%
Median $132,300
Mean $134,390
Employed 1,450
Greensboro, NC
same
Median $132,230
Mean $136,110
Employed 820
Pittsburgh, PA
-9.1%
Median $119,630
Mean $123,580
Employed 1,980
Newark, NJ
+24.1%
Median $163,340
Mean $162,620
Employed 21,680
St. Paul, MN
+1.4%
Median $133,370
Mean $137,660
Employed 4,900

See nurse practitioners pay in every covered city.

Take-home pay calculator

Estimate your net pay after federal, state, and FICA taxes. Adjust filing status and allowances for your situation.

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Gross annual income $131,580 / year
$131,580
Federal income tax 2024 brackets, Single filing
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State income tax Missouri (MO)
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FICA (Social Security + Medicare) 7.65% up to wage base
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Pre-tax deductions 401(k), HSA, etc.
$0
Take-home pay (annual) After all taxes
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Take-home per paycheck Monthly
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Effective tax rate Total tax ÷ gross income
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Estimates use 2024 federal tax brackets, FICA rates (6.2% SS up to $168,600, 1.45% Medicare + 0.9% >$200k), and state rates from Tax Foundation. Does not include local taxes, AMT, or tax credits. Consult a tax professional for actual liability.

Definitions used on this page

Annual median wage
The wage that half of the people in this occupation earn more than and half earn less than, for one year of work.
Annual mean wage
The average of all reported wages. It is higher than the median when a few very high earners pull it up.
Percentiles
The 10th percentile is the wage below which 10% of workers fall; the 90th is the wage above which only 10% rise. The gap between them shows how wide the pay range is.
Employment
The estimated number of jobs in this occupation in the metropolitan area, not the number of residents who hold it.

Sources and limits

Wages describe the metropolitan area, while rent and income describe the city boundaries. The two areas do not cover exactly the same ground. Wages are also averaged across a year and across every industry, so a specific employer can differ widely from the median shown here.